Home Home McDonald's - West Main Street Share 2465 West Main Street Tupelo, MS 38801 (662) 841-6800 Hours: Monday - Sunday 6:00 a.m. - 11:00 p.m., Friday - Saturday 6:00 a.m. - 1:00 a.m. Website Save McDonald's - West Main Street2465 West Main Street Tupelo, MS 38801DetailsOpen in Google Maps Map Overview McNuggets, apple pie, McFlurries Cuisines Fast Food
